Clinically Proven.
Visibly Transformative.
Experience the Dr. Denese difference with high-potency, bio-identical formulations engineered to visibly transform your skin's architecture, firmness, and glow.
Best Sellers
Skincare that delivers. Formulated with the best ingredients at the right percentages to bring you clearly visible results.
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Best SellerDr. Denese Advanced Firming Facial Pads
Regular price From $ 65.00Regular priceUnit price / perSale price From $ 65.00 -
Best SellerDr. Denese HydroShield®Hydrating Dream Cream
Regular price From $ 49.00Regular priceUnit price / per$ 65.00Sale price From $ 49.00Sale -
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Regular price From $ 49.00Regular priceUnit price / per$ 49.00Sale price From $ 49.00 -
Best SellerDr. Denese Pore Refining Toner
Regular price $ 19.99Regular priceUnit price / perSale price $ 19.99
"I formulate for results, not for hope."
As one of the first doctors to specialize in anti-aging medicine, Dr. Adrienne Denese, M.D., Ph.D., brings Harvard and Cornell-educated precision to every formula. At SkinScience Labs, we use the highest percentage of active, bio-identical ingredients the formulation can bear to visibly transform your skin's architecture.
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The 198% Breakthrough
Independent instrumental clinical studies prove our HydroShield® Ultra Moisturizing Face Serum delivers a staggering 198% increase in skin hydration in just 15 minutes. Don't just moisturize your wrinkles—biologically reset your skin's lipid barrier.
Shop the #1 Serum
On Sale Now
Transformative results, exceptional value. Discover limited-time savings on our award-winning, clinical-grade skincare.
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HydroShield Body Emulsion with Exosome
Regular price $ 59.00Regular priceUnit price / per$ 79.00Sale price $ 59.00Sale -
Dr. Denese Neck & Chin Tightening Serum
Regular price $ 66.75Regular priceUnit price / per$ 89.00Sale price $ 66.75Sale -
Dr. Denese HydroShield Face Emulsion with Exosome
Regular price $ 79.00Regular priceUnit price / per$ 99.00Sale price $ 79.00Sale
Explore Our Range of Products
New Arrivals
The newest breakthroughs from SkinScience Labs. Advanced, medical-grade formulations designed to tackle your toughest aging concerns.
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Dr. Denese Wrinkle Lost Patches - Forehead 2 Patches
Regular price $ 39.00Regular priceUnit price / perSale price $ 39.00 -
Dr. Denese Wrinkle Lost Patches for Eyes 3 Sets
Regular price $ 39.00Regular priceUnit price / perSale price $ 39.00 -
Dr. Denese Glow Younger Vitamin C Foundation
Regular price $ 69.00Regular priceUnit price / perSale price $ 69.00 -
Dr. Denese MegaLips Peptide Lip Oil 0.2 oz
Regular price $ 39.00Regular priceUnit price / per$ 39.00Sale price $ 39.00
From the blog
Our Blogs
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The Lipid Deficit: Why Your Luxury Cream is Fai...
In my years of research at Harvard and Cornell, I discovered a fundamental truth that the multi-billion dollar beauty industry often ignores: You cannot hydrate a surface that cannot hold...
The Lipid Deficit: Why Your Luxury Cream is Fai...
In my years of research at Harvard and Cornell, I discovered a...
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The Clinical Magic of Occlusion: An Overnight T...
As a physician, I am rarely swept off my feet by fleeting skincare trends. My standard for efficacy is rooted in cellular biology and measurable results. However, the physiologic ingenuity...
The Clinical Magic of Occlusion: An Overnight T...
As a physician, I am rarely swept off my feet by fleeting...
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The Collagen Conundrum: Why Your Skin Still Lov...
While it is true that you cannot simply "paint" new collagen onto your face to replace the structural fibers you lost in your thirties, dismissing collagen as an ingredient is...
The Collagen Conundrum: Why Your Skin Still Lov...
While it is true that you cannot simply "paint" new collagen onto...
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Spring Skincare Reset: Help Skin Recover and Glow!
As the weather shifts from cold, dry winter to warmer, more humid spring days, your skin’s needs change too. Seasonal transitions affect hydration levels, oil production, and barrier function, so...
Spring Skincare Reset: Help Skin Recover and Glow!
As the weather shifts from cold, dry winter to warmer, more humid...
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NATIONAL LIP APPRECIATION DAY! The Science of ...
As a physician, I often tell my patients that the skin on your lips is one of the most unique and vulnerable terrains on your body... Understanding how to choose...
NATIONAL LIP APPRECIATION DAY! The Science of ...
As a physician, I often tell my patients that the skin on...
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The Cellular Whisperers: Why Peptides are the D...
In the medical world, we often call them "biological messengers." In the vanity world, we call them "hope in a bottle." The truth lies somewhere in the middle: they are...
The Cellular Whisperers: Why Peptides are the D...
In the medical world, we often call them "biological messengers." In the...
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Why Is My Hair So Staticky Suddenly This Winter?
Introducing a new educational series for our customers and fans: Skincare 101 with Dr. Adrienne Denese, MD PhD "Knowledge is the first step to your most beautiful skin. Every...
Why Is My Hair So Staticky Suddenly This Winter?
Introducing a new educational series for our customers and fans: Skincare...
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The All Important Skin Lipid Barrier
Think of the skin barrier as a brick wall shielding the body living structure made of cells, lipids, water-binding molecules and microbial life. It’s a visual that works beautifully in...
The All Important Skin Lipid Barrier
Think of the skin barrier as a brick wall shielding the body...
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The Molecular Sandblaster: How Glycolic Acid Re...
If Retinol is the "biological software update" for your skin, Glycolic Acid is the high-speed demolition crew. It doesn't wait for your cells to decide to turn over; it goes...
The Molecular Sandblaster: How Glycolic Acid Re...
If Retinol is the "biological software update" for your skin, Glycolic Acid...
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Light Therapy Can Provide Full Body Healing
Feb 22nd, 2023 Denise Ryan Celluma / BioPhotas Light therapy can go beyond skin health, treating general pain conditions like arthritis, muscle spasm and joint pain as well. While many...
Light Therapy Can Provide Full Body Healing
Feb 22nd, 2023 Denise Ryan Celluma / BioPhotas Light therapy can go...
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Skin Age Reversed 13 Years in Just 9 Months by ...
While this habit change may have dramatic effects, there are natural substances that can help as well BETTER LIVING While claims of anti-aging made by many cosmetic makers are often...
Skin Age Reversed 13 Years in Just 9 Months by ...
While this habit change may have dramatic effects, there are natural substances...






