Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
Dr. Denese HydroShield® Ultra Moisturizing Face Serum
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  • Doctor developed
  • Clinically tested
  • PETA cruelty free
  • Made in USA

Join 20 million+ women who have transformed their skin with Dr. Denese

Multiple QVC Customer Choice Award winnerQVC Clean Beauty

HydroShield® Ultra Moisturizing Face Serum

Our Hydroshield® Serum, a multiple QVC Customer Choice Award winner, is a supercharged hydrating serum that locks in moisture to drastically reduce the look of dry lines and wrinkles and plumps the appearance of skin.

198%
more skin surface lipids after 15 minutes
97.7%
saw eye lines visibly reduced
100%
skin has a radiant glow

Instrumental clinical study (15 minutes) and independent consumer study, 21 days. See the studies

Size — 0.5 oz.Price per oz. shown
Purchase options
$29 $49
30-Day Money-Back Guarantee
Use the whole jar. If you don't see results, we refund you.

Product details

Why it is different

Who is it for: Suitable for any skin types from dry to normal. Oily skin or combination skin may want to target their dry or rough spots.

Why is it different: Our Hydroshield®Serum is based on years of medical research that identified a unique and proprietary technology that we named Hydroshield® Technology, that uses lipids that are virtually identical to the skin’s own lipids. As we age, skin lipids decline, leaving the skin dry and line prone. Our proprietary Hydroshield® Technology™ supplies a balance of skin identical lipids, ceramides and Essential Fatty Acids to help the skin lipid barrier to function at a much younger level. Once hydration and moisture is locked into the skin, the appearance of dry lines and wrinkles improve rapidly.

See what some of our viewers had to say about this product:

Can't live without! 
"The best of the best...can't live without, makes your face feel like silk." Review by: Grasta

Extremely Effective on Sensitive Combo Skin
"This product is nothing short of amazing. My personal results are impressive, nasal-labial folds plumper, forehead lines dramatically diminished and marionette lines appear shorter. This product is so crazy good and a staple in my nightly skin care regimen."  Review by:  iQgirl

The best Hydration. Ever!
I have used Hydroshield faithfully for over one year. My skin is radiant. I wouldn't be without this product." Review by: Dawniee

Dr. Denese HydroShield® Ultra Moisturizing Face Serum
From the clinical testing of this product. Individual results vary.

Clinical studies

The results, by the numbers

Clinical Studies:

Instrumental Clinical Study (instant):

  • 198% increase in skin surface lipids after 15 minutes

Instrumental Cutometer Measured Clinical Study (42 days):

  • statistically significant increase in skin tightness and firmness

Independent Consumer Study (21 days):

  • In 100% cases: skin has radiant glow
  • In 100% cases: skin appears more plump
  • In 100% cases: skin feels more supple, soft and plump
  • In 97.7% cases: lines, wrinkles and crepiness around the eye visibly reduced
  • In 97.7% cases: lines, wrinkles and crepiness around the mouth visibly reduced

Watch

Dr. Denese explains it herself

How to use

How to use

Usage: In the morning and evening, apply to clean face before your day cream or night cream. Let the serum penetrate for five to seven minutes, until it turns matte. If you are oily or normal, apply only around the eyes, cheeks and neck. Even if you are oily, the eye area skin is almost always dry.

Ingredients

What is inside

Retinol

Helps firm the skin, reduce the look of fine lines and wrinkles and stimulate collagen production.

oothing of lines and wrinkles and improve tone and elasticity

Ceramides

Helps mimic your skin's lipid barrier, prevents water loss, improves suppleness, skin texture while calming the skin

Ingredients: Dimethicone, Ceramide NG, Retinol, Tocopherol, Linoleic Acid, Linolenic Acid, Ethylhexyl Cocoate, Lecithin, Glycolipids, Phenoxyethanol

  • Always Doctor developed
  • Always Clinically tested
  • Always Visible results
  • Always High percentages of actives
  • Always PETA cruelty free
  • Always Manufactured in USA

Sent in by customers

Their own photos, their own words

Photographs customers uploaded with their reviews, across the range. The words are theirs — shortened at a full stop where a card ran long, never rewritten.

Photographs and reviews submitted by customers and published with their permission. Individual results vary.

Dr. Denese Simple Steps skin care program

Where this product fits in your routine

Simple morning routine

  1. 1
    Build Lipid Barrier

    Keeps water from leaving the skin. Hydrated skin is healthy skin.

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  2. 2
    Protect & Correct

    SPF 30 or 40 — rain or shine, summer and winter. 90% of skin aging is caused by daily sun exposure.

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Simple evening routine

  1. 1
    Cleanse & Tone

    A pH-balanced, non-drying cleanser — skip the soap — then a toner for what it missed.

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  2. 2
    Exfoliate & Purify

    Stimulates cellular turnover and lets the actives that follow reach their destination.

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  3. 3
    Stimulate Cellular Performance

    A thin, water-consistency serum that encourages the skin's own collagen building.

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  4. 4
    Build Lipid Barrier

    Lipid-based serum with ceramides, retinol, antioxidants and essential fatty acids.

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  5. 5
    Seal & Maintain

    Finish with your night cream to seal the work in.

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Complete the routine

Award Winning Power Trio

The Firming Facial Pads, the HydroShield® Serum and the Hydrating Dream Cream as one starter kit.

$79$127
Shop the trio

Reviews

What customers say

A doctor formulated this, not a marketing team.

Who made it

A doctor formulated this, not a marketing team.

Adrienne Denese, M.D., Ph.D. — Harvard and Cornell trained, and one of the first physicians to specialise in anti-aging medicine. Every formula leaves SkinScience Labs with the highest percentage of active, bio-identical ingredients it can carry. Over 20 million products sold worldwide.

“I formulate for results, not for hope.”

Adrienne Denese, M.D., Ph.D.