New — The Award Winning Power Trio

Three Best Sellers.
One Biological Reset.

Over 20 million products sold worldwide

The Firming Facial Pads, HydroShield® Ultra Serum and HydroShield® Dream Cream — the exact three-step protocol Dr. Denese built her practice on, together for the first time.

  • +31% firmer skin in 28 days — instrumental Cutometer® study
  • 198% more skin lipids in just 15 minutes
  • 100% of participants measured +23% tightness in 4 weeks
$79 $127 Save $48 · 38% off

Only 450 kits in this first production run

  • Free U.S. shipping over $75
  • Formulated by Harvard-trained Dr. Denese
  • As seen on QVC®
Dr. Denese Award Winning Power Trio — Advanced Firming Facial Pads, HydroShield Ultra Moisturizing Face Serum and HydroShield Dream Cream
Harvard & Cornell Educated MD, PhD
Proven Results Independent Clinical Studies
20M+ Products Sold Multi-Award Winning
Cruelty-Free QVC Clean Beauty

Best Sellers

Skincare that delivers. Formulated with the best ingredients at the right percentages to bring you clearly visible results.

1 of 4
Dr. Adrienne Denese at work formulating skincare
The Science of Skincare

"I formulate for results, not for hope."

As one of the first doctors to specialize in anti-aging medicine, Dr. Adrienne Denese, M.D., Ph.D., brings Harvard and Cornell-educated precision to every formula. At SkinScience Labs, we use the highest percentage of active, bio-identical ingredients the formulation can bear to visibly transform your skin's architecture.

#1 Anti-Aging Brand on QVC
20M+ Products Sold Worldwide
Discover Her Story

The 198% Breakthrough

Independent instrumental clinical studies prove our HydroShield® Ultra Moisturizing Face Serum delivers a staggering 198% increase in skin hydration in just 15 minutes. Don't just moisturize your wrinkles—biologically reset your skin's lipid barrier.

Shop the #1 Serum
HydroShield Ultra Moisturizing Face Serum
198% INCREASE HYDRATION in 15 minutes

On Sale Now

Transformative results, exceptional value. Discover limited-time savings on our award-winning, clinical-grade skincare.

Simple Steps

Morning and evening skincare routines

Learn More
Responsive image

Explore Our Range of Products

New Arrivals

The newest breakthroughs from SkinScience Labs. Advanced, medical-grade formulations designed to tackle your toughest aging concerns.

1 of 4
Skinscience

August’s Featured Product

View All Products

From the blog

Our Blogs

1 of 12