Five Eye Problems.
One Clinical Answer.
Puffiness, dark circles, crepiness, dry crossed lines and crow’s feet — the five things concealer cannot fix. The delicate skin around your eyes does not need another moisturizer, it needs a targeted clinical intervention.
- 27% less visible crow’s feet and 20% fewer lines under the eyes in 21 days
- 19% less puffiness, 18% lighter dark circles — Independent Expert Grading Study
- 100% of cases improved in every single category measured
Sale ends Sunday, Aug 23 at 11:59pm ET — no code needed
- Free U.S. shipping over $75
- Formulated by Harvard-trained Dr. Denese
- Clean Beauty — no parabens, sulfates or dyes
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Best SellerDr. Denese HydroShield®Hydrating Dream Cream
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Best SellerDr. Denese Advanced Firming Facial Pads
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Best SellerDr. Denese HydroShield® Ultra Moisturizing Face Serum
Regular price From $ 29.00Regular priceUnit price per$ 49.00Sale price From $ 29.00Sale -
Best SellerDr. Denese Pore Refining Toner
Regular price $ 20.00Regular priceUnit price per
"I formulate for results, not for hope."
As one of the first doctors to specialize in anti-aging medicine, Dr. Adrienne Denese, M.D., Ph.D., brings Harvard and Cornell-educated precision to every formula. At SkinScience Labs, we use the highest percentage of active, bio-identical ingredients the formulation can bear to visibly transform your skin's architecture.
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The 198% Breakthrough
Independent instrumental clinical studies prove our HydroShield® Ultra Moisturizing Face Serum delivers a staggering 198% increase in skin hydration in just 15 minutes. Don't just moisturize your wrinkles—biologically reset your skin's lipid barrier.
Shop the #1 Serum
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Dr. Denese No Offense 72 Hr Body Deodorant 3.4 oz.
Regular price $ 29.00Regular priceUnit price per$ 39.00Sale price $ 29.00Sale -
Dr. Denese Peel & Glow Rx Vitamin C Face Paste & AHA Peel Drops Set
Regular price $ 85.00Regular priceUnit price per$ 135.00Sale price $ 85.00Sale
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Award Winning Power Trio
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30 GREENS AND REDS GUMMIES
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Dr. Denese HydroShield Eye Emulsion with Exosome
Regular price $ 69.00Regular priceUnit price per$ 69.00Sale price $ 69.00 -
Dr. Denese Wrinkle Lost Patches
Regular price $ 39.00Regular priceUnit price per
Our Blogs
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The 5 Biggest Collagen Destroyers (And How to S...
The encouraging reality of dermatological science is that collagen loss is not entirely out of your control. By understanding the biochemical mechanisms that breakdown this critical structural network, you can...
The 5 Biggest Collagen Destroyers (And How to S...
The encouraging reality of dermatological science is that collagen loss is not...
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Cortisol, The Single Most Aging Hormone We Have
Cortisol is the pro aging hormone; its activity produces every single sign of what we call “aging”... Bottom line: chronically elevated cortisol is aging you faster and making you sicker than...
Cortisol, The Single Most Aging Hormone We Have
Cortisol is the pro aging hormone; its activity produces every single sign...
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The Science of the "Second Skin": Unlocking the...
When it comes to hydrogel masks—such as our HydroBurst Eye Mask, we aren’t just talking about a simple sheet soaked in serum. We are talking about a sophisticated drug-delivery system...
The Science of the "Second Skin": Unlocking the...
When it comes to hydrogel masks—such as our HydroBurst Eye Mask, we...
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The Science of the Pout: Understanding Lip Anat...
Unlike the skin on your face, your lips lack the protective layer of oil glands and have a significantly thinner stratum corneum—the outermost barrier. This makes them exceptionally prone to...
The Science of the Pout: Understanding Lip Anat...
Unlike the skin on your face, your lips lack the protective layer...
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The Multitasking Marvel: A Clinical Perspective...
What makes niacinamide truly fascinating is its versatility. It is a "multitasking" molecule that addresses multiple physiological pathways simultaneously.
The Multitasking Marvel: A Clinical Perspective...
What makes niacinamide truly fascinating is its versatility. It is a "multitasking"...
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GLYPHOSATE: The Weed Killer That Can Kill You
For decades, the standard scientific narrative was that glyphosate is perfectly safe for humans because it targets a specific metabolic pathway (the shikimate pathway) that exists in plants but not...
GLYPHOSATE: The Weed Killer That Can Kill You
For decades, the standard scientific narrative was that glyphosate is perfectly safe...
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Oral Collagen: Does Your Skin Know The Differe...
As we age, our body's natural collagen production drops by about 1% to 1.5% every year. By ingesting high-quality oral collagen, you deliver the structural building blocks directly through the...
Oral Collagen: Does Your Skin Know The Differe...
As we age, our body's natural collagen production drops by about 1%...
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The Triumph of Merit and Freedom: A 250th Anniv...
When I finally arrived on these shores, I had nothing but forty dollars in my pocket and a mind ready to learn. In any other nation, that would be the...
The Triumph of Merit and Freedom: A 250th Anniv...
When I finally arrived on these shores, I had nothing but forty...
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Toxic Beauty: The Secret History of 18th-Centur...
Have you ever wondered how far people would go for the ultimate beauty trend?
Toxic Beauty: The Secret History of 18th-Centur...
Have you ever wondered how far people would go for the ultimate...
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The Golden Standard: Why Vitamin C Belongs in Y...
Vitamin C is not just a trend; it is a clinical necessity for anyone serious about skin health. It is one of the few ingredients that addresses defense, repair, and...
The Golden Standard: Why Vitamin C Belongs in Y...
Vitamin C is not just a trend; it is a clinical necessity...
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The Silent Architect of Aging: Why Sunlight is ...
Did you know that up to 90% of visible skin aging is caused by the sun? Discover the hidden dangers of UVA and UVB rays, and learn why switching to...
The Silent Architect of Aging: Why Sunlight is ...
Did you know that up to 90% of visible skin aging is...
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The Moisture Magnet: A Doctor’s Guide to Hyalur...
Patients come to me asking for the "fountain of youth" in a bottle. While I haven't found a literal fountain yet, Hyaluronic Acid (HA) is about as close as we...
The Moisture Magnet: A Doctor’s Guide to Hyalur...
Patients come to me asking for the "fountain of youth" in a...
