Labor Day Sale · 9/4 – 9/7 only

Buy More. Save More.

The more you build your routine, the less you pay. Your cart picks the discount — up to 40% off your entire order, storewide.

Spend $50+ 20% off
Spend $100+ 30% off
Spend $150+ 40% off
Sale ends in
00Days 00Hrs 00Min 00Sec
Shop the Sale No code needed — the discount applies in your cart.
Clinically proven results · Over 20 million products sold worldwide
Buy More. Save More.
Harvard & Cornell Educated MD, PhD
Proven Results Independent Clinical Studies
20M+ Products Sold Multi-Award Winning
Cruelty-Free QVC Clean Beauty

Best Sellers

Skincare that delivers. Formulated with the best ingredients at the right percentages to bring you clearly visible results.

1 of 4
Dr. Adrienne Denese at work formulating skincare
The Science of Skincare

"I formulate for results, not for hope."

As one of the first doctors to specialize in anti-aging medicine, Dr. Adrienne Denese, M.D., Ph.D., brings Harvard and Cornell-educated precision to every formula. At SkinScience Labs, we use the highest percentage of active, bio-identical ingredients the formulation can bear to visibly transform your skin's architecture.

#1 Anti-Aging Brand on QVC
20M+ Products Sold Worldwide
Discover Her Story

The 198% Breakthrough

Independent instrumental clinical studies prove our HydroShield® Ultra Moisturizing Face Serum delivers a staggering 198% increase in skin hydration in just 15 minutes. Don't just moisturize your wrinkles—biologically reset your skin's lipid barrier.

Shop the #1 Serum
HydroShield Ultra Moisturizing Face Serum
198% INCREASE HYDRATION in 15 minutes

On Sale Now

Transformative results, exceptional value. Discover limited-time savings on our award-winning, clinical-grade skincare.

Simple Steps

Morning and evening skincare routines

Learn More
Responsive image

Explore Our Range of Products

New Arrivals

The newest breakthroughs from SkinScience Labs. Advanced, medical-grade formulations designed to tackle your toughest aging concerns.

1 of 4
Skinscience

September’s Featured Product

View All Products

From the blog

Our Blogs

1 of 12