Your Treasure Awaits.
40% Off Everything.
Every formula in our lineup is a treasure worth finding — clinical serums, peptide treatments, and barrier-repairing creams, all part of the hunt.
No exclusions. This weekend only, take 40% OFF the entire store — every product, every collection, everything.
Sale Ends Sunday, August 16th at 11:59 PM EDT
Best Sellers
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Best SellerDr. Denese HydroShield®Hydrating Dream Cream
Regular price From $ 29.40Regular priceUnit price per$ 49.00Sale price From $ 29.40Sale -
Best SellerDr. Denese Advanced Firming Facial Pads
Regular price From $ 17.40Regular priceUnit price per$ 29.00Sale price From $ 17.40Sale -
Best SellerDr. Denese HydroShield® Ultra Moisturizing Face Serum
Regular price From $ 29.00Regular priceUnit price per$ 49.00Sale price From $ 29.00Sale -
Best SellerDr. Denese Pore Refining Toner
Regular price $ 12.00Regular priceUnit price per$ 20.00Sale price $ 12.00Sale
"I formulate for results, not for hope."
As one of the first doctors to specialize in anti-aging medicine, Dr. Adrienne Denese, M.D., Ph.D., brings Harvard and Cornell-educated precision to every formula. At SkinScience Labs, we use the highest percentage of active, bio-identical ingredients the formulation can bear to visibly transform your skin's architecture.
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The 198% Breakthrough
Independent instrumental clinical studies prove our HydroShield® Ultra Moisturizing Face Serum delivers a staggering 198% increase in skin hydration in just 15 minutes. Don't just moisturize your wrinkles—biologically reset your skin's lipid barrier.
Shop the #1 Serum
On Sale Now
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Dr. Denese No Offense 72 Hr Body Deodorant 3.4 oz.
Regular price $ 29.00Regular priceUnit price per$ 39.00Sale price $ 29.00Sale -
Dr. Denese Peel & Glow Rx Vitamin C Face Paste & AHA Peel Drops Set
Regular price $ 85.00Regular priceUnit price per$ 135.00Sale price $ 85.00Sale
Explore Our Range of Products
New Arrivals
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30 GREENS AND REDS GUMMIES
Regular price $ 47.40Regular priceUnit price per$ 79.00Sale price $ 47.40Sale -
Dr. Denese HydroShield Eye Emulsion with Exosome
Regular price $ 41.40Regular priceUnit price per$ 69.00Sale price $ 41.40Sale -
Dr. Denese Wrinkle Lost Patches
Regular price $ 23.40Regular priceUnit price per$ 39.00Sale price $ 23.40Sale -
Dr. Denese Glow Younger Vitamin C Foundation
Regular price $ 41.40Regular priceUnit price per$ 69.00Sale price $ 41.40Sale
Our Blogs
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Cortisol, The Single Most Aging Hormone We Have
Cortisol is the pro aging hormone; its activity produces every single sign of what we call “aging”... Bottom line: chronically elevated cortisol is aging you faster and making you sicker than...
Cortisol, The Single Most Aging Hormone We Have
Cortisol is the pro aging hormone; its activity produces every single sign...
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The Science of the "Second Skin": Unlocking the...
When it comes to hydrogel masks—such as our HydroBurst Eye Mask, we aren’t just talking about a simple sheet soaked in serum. We are talking about a sophisticated drug-delivery system...
The Science of the "Second Skin": Unlocking the...
When it comes to hydrogel masks—such as our HydroBurst Eye Mask, we...
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The Science of the Pout: Understanding Lip Anat...
Unlike the skin on your face, your lips lack the protective layer of oil glands and have a significantly thinner stratum corneum—the outermost barrier. This makes them exceptionally prone to...
The Science of the Pout: Understanding Lip Anat...
Unlike the skin on your face, your lips lack the protective layer...
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The Multitasking Marvel: A Clinical Perspective...
What makes niacinamide truly fascinating is its versatility. It is a "multitasking" molecule that addresses multiple physiological pathways simultaneously.
The Multitasking Marvel: A Clinical Perspective...
What makes niacinamide truly fascinating is its versatility. It is a "multitasking"...
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GLYPHOSATE: The Weed Killer That Can Kill You
For decades, the standard scientific narrative was that glyphosate is perfectly safe for humans because it targets a specific metabolic pathway (the shikimate pathway) that exists in plants but not...
GLYPHOSATE: The Weed Killer That Can Kill You
For decades, the standard scientific narrative was that glyphosate is perfectly safe...
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Oral Collagen: Does Your Skin Know The Differe...
As we age, our body's natural collagen production drops by about 1% to 1.5% every year. By ingesting high-quality oral collagen, you deliver the structural building blocks directly through the...
Oral Collagen: Does Your Skin Know The Differe...
As we age, our body's natural collagen production drops by about 1%...
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The Triumph of Merit and Freedom: A 250th Anniv...
When I finally arrived on these shores, I had nothing but forty dollars in my pocket and a mind ready to learn. In any other nation, that would be the...
The Triumph of Merit and Freedom: A 250th Anniv...
When I finally arrived on these shores, I had nothing but forty...
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Toxic Beauty: The Secret History of 18th-Centur...
Have you ever wondered how far people would go for the ultimate beauty trend?
Toxic Beauty: The Secret History of 18th-Centur...
Have you ever wondered how far people would go for the ultimate...
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The Golden Standard: Why Vitamin C Belongs in Y...
Vitamin C is not just a trend; it is a clinical necessity for anyone serious about skin health. It is one of the few ingredients that addresses defense, repair, and...
The Golden Standard: Why Vitamin C Belongs in Y...
Vitamin C is not just a trend; it is a clinical necessity...
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The Silent Architect of Aging: Why Sunlight is ...
Did you know that up to 90% of visible skin aging is caused by the sun? Discover the hidden dangers of UVA and UVB rays, and learn why switching to...
The Silent Architect of Aging: Why Sunlight is ...
Did you know that up to 90% of visible skin aging is...
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The Moisture Magnet: A Doctor’s Guide to Hyalur...
Patients come to me asking for the "fountain of youth" in a bottle. While I haven't found a literal fountain yet, Hyaluronic Acid (HA) is about as close as we...
The Moisture Magnet: A Doctor’s Guide to Hyalur...
Patients come to me asking for the "fountain of youth" in a...
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The Biological Time Machine: How Retinol Rewire...
In the world of dermatology, Retinol is the undisputed heavyweight champion—not because it’s a trendy marketing buzzword, but because it is one of the few ingredients that actually speaks the...
The Biological Time Machine: How Retinol Rewire...
In the world of dermatology, Retinol is the undisputed heavyweight champion—not because...
