Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate


45 reviews

See what our Customers are saying about Wrinkle Rx 76% Peptide Solution Concentrate:


 Wonderful serum

 "I think this serum is the best ever, I use it faithfully day and night as I have seen great improvement to my skin since I started using it! I always buy 2 of these so I never run out!" Review by: Shirley V.

 Wrinkle Eraser! 

 "I use this product daily. It is highly rich in peptides and has made a huge difference in the firmness of my skin. I feel certain I'd have a lot more lines and wrinkles if I stopped using it. I highly recommend." Review by: Kennette

  Must Have

 "This is one of my "can't live without" products I have been using this since 2013. I use this morning and night it definitely reduces lines and wrinkles." Review by: Patricia



What is it: A true technological breakthrough! Perhaps the highest concentration  of peptides and neuropeptides  in the marketplace. Just for comparison: a typical, high end peptide serum in the marketplace contains between 3-6% of peptide solution, a handful serums are around 20%. Ours is 76%!


What does this mean to you? In one word: performance. This serum will drastically improve the look of wrinkles, deep etched in lines or lighter dynamic lines and  wrinkles that are just starting.  It is especially valuable around the eyes, including your upper eye lids. It visibly reduces lines around the eyes and firms the appearance of the upper and lower eye lids. It also changes the appearance of skin texture and skin firmness. This serum teaches your skin how to act younger.

Who is it for: If you have lines, wrinkles, crow’s feet if you want a resolution to the multitudes of lines and wrinkles on your face: this is the serum.

Why is it different: A true technological breakthrough that concentrates an unprecedented 76% peptides and neuropeptides into a serum. One of the most expensively made serums in the marketplace.  In an independent study: 100% subjects reported: This serum did the most for them as compared to all other products they ever used. Just think about how many jars and bottles of skin care you have at home?

Research Results:

Independent Consumer Study:

  • 100% subjects found: visible improvement in Crow's feet
  • 100% subjects reported: that this serum did perhaps the most for them compared to all other serums they have ever used
  • 90% subjects found that this serum succeeded where others failed

Usage: Apply once or twice a day to clean skin. Use it as your first layer of skin care. Follow with a heavier serum such as e.g. HydroShield. Follow with eye cream of your choice.

 Made without parabens or dyes. No animal testing.

Ingredients: Water, Cyclomethicone, Caprylic/ Capric Triglyceride, Glycerin, Dipropylene Glycol, Sodium Hyaluronate, Dimethicon/Vinyl Dimethicone Crosspolymer, PEG/PPG-19/19 Dimethicone, Hydrolyzed Rice Protein, Butylene Glycol, Lecithin, Acetyl Glutamyl Heptapeptide-1, Malus domestica fruit cell culture, Rh-Polypeptide-7, Tripeptide-1, Malus domestica fruit cell culture, Caprooyl- Tetrapeptide-3, Avena Sativa (Oat) Kernel Protein, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-8, Palmitoyl Tripeptide-5, Oligopeptide-4, Diacetyl Boldine, Adenosine, Arginine, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Guanidine, Glucose, Dextran, BIS-PEG-18 Methyl Ether Dimethyl Silane, Dimethiconol, PPG-26-Buteth- 26, PEG-40 Hydrogenated Castor Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Phosphate, EDTA, Sodium Chloride, Sodium Polyacrylate, Methyl Gluceth-20, Disodium EDTA, Carbomer, Polysorbate 20, Polysorbate 80, Xanthan Gum, Citrus Aurantium Amara (Bitter Orange) Peel Oil, Sodium Polyacry- late, PVM/MA Copolymer, Caprylyl Glycol, Phenoxyethanol.

Customer Reviews
5.0 Based on 45 Reviews
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Filter Reviews:
A Dr Denese SkinScience Customer
Sue K.
United States United States
I love this product

I noticed gradual improvement in the look and feel of my skin. It looks and feels so soft and fine lines virtually gone especially around the eyes. I only wish you would bring back SuperSundays so I could purchase more as this is a bit pricey!

Lorene M.
United States United States

I love using this daily after I wash my face with Dr. Denese cleanser. It improves the quality of my skin and diminishes wrinkles. It is an excellent product. I follow with your other line of products that are excellent for my fair skin.

United States United States
Peptides work!

This product does what it says and tackles wrinkles over time. It soaks right into my skin, smoothing it, without pilling.

Marilyn R.
United States United States
Wrinkle RX 76% Peptide Solution

If I could give this 10 stars, I would. This product, above all, makes the biggest difference in brightening and anti aging! The only problem I have is that Dr. Denise has SO MANY great products, I can't use them ALL AT ONCE! I just re-ordered it yesterday, I wish it weren't "quite so expensive"!!

Laurie H.
United States United States
Wrinkle RX 76% peptide.

Have been using Dr. Denese products for over 10 years. All of her products are exceptional. This product is superb! Can’t believe how good my skin looks.

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