Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate

Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate

#8200571


Regular price $ 162.00
48 reviews
Save $ -162.00
207 in stock

A true technological breakthrough! Perhaps the highest concentration of peptides and neuropeptides in the marketplace. This serum will drastically improve the look of wrinkles, deep etched in lines or lighter dynamic lines and wrinkles that are just starting. It is especially valuable around the eyes, including your upper eye lids.

Who is it for: If you have lines, wrinkles, crow’s feet if you want a resolution to the multitudes of lines and wrinkles on your face: this is the serum.

Why is it different: A true technological breakthrough that concentrates an unprecedented 76% peptides and neuropeptides into a serum. One of the most expensively made serums in the marketplace. In an independent study: 100% subjects reported: This serum did the most for them as compared to all other products they ever used. Just think about how many jars and bottles of skin care you have at home?

See what some of our QVC Customers had to say about this product:

Wonderful serum
"I think this serum is the best ever, I use it faithfully day and night as I have seen great improvement to my skin since I started using it! I always buy 2 of these so I never run out!" Review by: Shirley V.

Wrinkle Eraser!
"I use this product daily. It is highly rich in peptides and has made a huge difference in the firmness of my skin. I feel certain I'd have a lot more lines and wrinkles if I stopped using it. I highly recommend." Review by:Kennette

Must Have
"This is one of my "can't live without" products I have been using this since 2013. I use this morning and night it definitely reduces lines and wrinkles." Review By: Patricia

Clinical Studies:

Independent Consumer Study:

  • 100% subjects found: visible improvement in Crow's feet.
  • 100% subjects reported: that this serum did perhaps the most for them compared to all other serums they have ever used
  • 90% subjects found that this serum succeeded where others failed

Usage: Apply once or twice a day to clean skin. Use it as your first layer of skin care. Follow with a heavier serum such as e.g. HydroShield. Follow with eye cream of your choice.


Free from: Parabens, sulfates, dyes, phthalates. No animal testing.

Ingredients: Water, Cyclomethicone, Caprylic/ Capric Triglyceride, Glycerin, Dipropylene Glycol, Sodium Hyaluronate, Dimethicon/Vinyl Dimethicone Crosspolymer, PEG/PPG-19/19 Dimethicone, Hydrolyzed Rice Protein, Butylene Glycol, Lecithin, Acetyl Glutamyl Heptapeptide-1, Malus domestica fruit cell culture, Rh-Polypeptide-7, Tripeptide-1, Malus domestica fruit cell culture, Caprooyl- Tetrapeptide-3, Avena Sativa (Oat) Kernel Protein, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-8, Palmitoyl Tripeptide-5, Oligopeptide-4, Diacetyl Boldine, Adenosine, Arginine, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Guanidine, Glucose, Dextran, BIS-PEG-18 Methyl Ether Dimethyl Silane, Dimethiconol, PPG-26-Buteth- 26, PEG-40 Hydrogenated Castor Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Phosphate, EDTA, Sodium Chloride, Sodium Polyacrylate, Methyl Gluceth-20, Disodium EDTA, Carbomer, Polysorbate 20, Polysorbate 80, Xanthan Gum, Citrus Aurantium Amara (Bitter Orange) Peel Oil, Sodium Polyacry- late, PVM/MA Copolymer, Caprylyl Glycol, Phenoxyethanol.

Product Detail

Who is it for: If you have lines, wrinkles, crow’s feet if you want a resolution to the multitudes of lines and wrinkles on your face: this is the serum.


Why is it different: A true technological breakthrough that concentrates an unprecedented 76% peptides and neuropeptides into a serum. One of the most expensively made serums in the marketplace. In an independent study: 100% subjects reported: This serum did the most for them as compared to all other products they ever used. Just think about how many jars and bottles of skin care you have at home?


See what some of our QVC Customers had to say about this product:



Wonderful serum
"I think this serum is the best ever, I use it faithfully day and night as I have seen great improvement to my skin since I started using it! I always buy 2 of these so I never run out!" Review by:Shirley V.

Wrinkle Eraser!
"I use this product daily. It is highly rich in peptides and has made a huge difference in the firmness of my skin. I feel certain I'd have a lot more lines and wrinkles if I stopped using it. I highly recommend." Review by: Kennette

Must Have
"This is one of my "can't live without" products I have been using this since 2013. I use this morning and night it definitely reduces lines and wrinkles." Review By: Patricia

Clinical Studies

Independent Consumer Study:

  • 100% subjects found: visible improvement in Crow's feet.
  • 100% subjects reported: that this serum did perhaps the most for them compared to all other serums they have ever used
  • 90% subjects found that this serum succeeded where others failed
  • Usage

    Usage: Apply once or twice a day to clean skin. Use it as your first layer of skin care. Follow with a heavier serum such as e.g. HydroShield. Follow with eye cream of your choice.

    Free from: Parabens, sulfates, dyes, phthalates. No animal testing.

    Ingredients

    Ingredients: Water, Cyclomethicone, Caprylic/ Capric Triglyceride, Glycerin, Dipropylene Glycol, Sodium Hyaluronate, Dimethicon/Vinyl Dimethicone Crosspolymer, PEG/PPG-19/19 Dimethicone, Hydrolyzed Rice Protein, Butylene Glycol, Lecithin, Acetyl Glutamyl Heptapeptide-1, Malus domestica fruit cell culture, Rh-Polypeptide-7, Tripeptide-1, Malus domestica fruit cell culture, Caprooyl- Tetrapeptide-3, Avena Sativa (Oat) Kernel Protein, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-8, Palmitoyl Tripeptide-5, Oligopeptide-4, Diacetyl Boldine, Adenosine, Arginine, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Guanidine, Glucose, Dextran, BIS-PEG-18 Methyl Ether Dimethyl Silane, Dimethiconol, PPG-26-Buteth- 26, PEG-40 Hydrogenated Castor Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Phosphate, EDTA, Sodium Chloride, Sodium Polyacrylate, Methyl Gluceth-20, Disodium EDTA, Carbomer, Polysorbate 20, Polysorbate 80, Xanthan Gum, Citrus Aurantium Amara (Bitter Orange) Peel Oil, Sodium Polyacry- late, PVM/MA Copolymer, Caprylyl Glycol, Phenoxyethanol.

    Why in this order?

    Based on state-of-the-art medical knowledge, I have identified six phases of skin care that you will need to complete every night to successfully address the eight visual signs of aging skin.

    1. Cleanse and Tone

    The cleansing phase is an important first step and I do not recommend using soap. The pH of soap can dry your skin. I also do not recommend water-free, leave-on cleansers, which can clog your pores. A good cleanser has a pH close to that of the skin and will not dry out your skin. After cleansing, I recommend using toner to remove the dirt the cleanser missed.

    CLEANSER: The best ingredients to seek out in this product are alpha- and beta-hydroxy acids, which are excellent cleaning agents, and other beneficial additions, such as vitamins C and E. However, the key isn't just the ingredients—you rinse them off very quickly—but finding a good cleanser that doesn't leave your skin feeling tight and dry. You should judge your cleanser based on the condition of your skin after you've washed, rinsed, and dried. Your face should feel fresh, clean, and comfortable, not dry or pulled.

    TONER: The same criteria apply. An effective toner will have a gentle astringency, yet it should leave your face feeling soft and refreshed. If your skin doesn't feel pulled and dry after you've applied it, it's the right product for you.

    2. Exfoliate and Purify

    The exfoliating phase is critical if you want flawless skin. Exfoliation stimulates cellular turnover and may improve skin thickness. It also removes dead cells on top of your skin, allowing skin care products to transport key ingredients to their destination. The exfoliating phase also provides one final opportunity to open up clogged pores before you move on to the other phases of your skin care routine.

    Try our glycolic acid peel pads, the Advanced Firming Facial Pads, with a 10 % strength solution. Clinical studies have shown significant collagen-stimulating and skin-thickness-building action at the right glycolic concentration at the right pH levels. Our Advanced Firming Facial Pads are made to these exact specifications. These pads also exfoliate your skin to perfection which is critical if you want flawless skin.

    Microdermabrasion Cream: You need this product for additional exfoliation once a week, or twice, if your skin has the tolerance for it. A good microdermabrasion cream should have a rich texture and contain abrasive particles—aluminum oxide or pumice is ideal—but the particles should be very small. Avoid products that contain large grains of any rough or sharp particles. The purpose of this step is to micropolish your face, not scratch it. And the cream should feel good. When you rinse it off, your face should not feel tight or dry, but rather smooth, soft, and soothed.

    3. Stimulate Cellular Performance

    SKIN-STIMULATING SERUM: The skin-stimulating phase encourages the skin's own collagen-building machinery and repair mechanism to soften the look of lines and wrinkles. This is ideally done with a thin water-consistency serum, rich in ingredients that easily permeate the skin. This step does not feel particularly moisturizing and it may leave your skin feeling dry and tingly.

    4. Build Lipid Barrier

    SKIN-BUILDING SERUM: The skin-building phase helps restore skin barrier functions via delivering essential nutrients to the skin. This is ideally done with lipid-based serums and contains high concentrations of lipid (fat) soluble vitamins, ceramides, antioxidants, retinol and essential fatty acids.

    With this regimen you are layering your face with all the rich ingredients that are so effective in fighting the signs of aging. You are rebuilding the all important skin lipid barrier to protect your skin from drying out and generating wrinkles.

    5. Seal and Maintain

    The skin-building phase helps prevent water loss via sealing the top layer of the skin with emollient lipids (step 4) while the skin-sealing phase (step 5) moisturizes and prevents water loss by sealing the skin. This is done with a cream with the right balance of lipids and humectants to help maintain and balance the moisture level in the skin to protect the skin from dryness.

    This final application of cream is to seal the skin and rebuild the lipid barrier. First and foremost, a cream should feel good. It should not leave your skin feeling dry and your skin should not remain shiny for hours after you've applied it. Look for the right level of lipids in the cream that is satisfying to your skin. Ceramides, EFAs, retinol, vitamins C and E, and hyaluronic acid are all excellent ingredients for this last step in your skin care program.

    6. Protect and Correct

    The skin-protection phase consists of using SPF 30 sun protection daily in the morning and throughout the day, rain or shine, every day of the year. Sun exposure is the most common cause of aging and with use of a good protective product, aging from sun damage can be reduced.

    Doctor Developed. Clinically Tested. Visible Results.
    High Percentages of Active Ingredients.
    PETA Cruelty Free. Manufactured in USA. 
    Free from:
    • Parabens 
    • Sulfates 
    • Dyes 
    • Phthalates
    • Formaldehyde
    • Mineral Oil
    • Triclosan 
    • Hydroquinone 
    • SLS & SLES
    • Oxybenzone
     

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    Customer Reviews
    5.0 Based on 48 Reviews
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    Filter Reviews:
    MD
    11/03/2020
    Madelyn D.
    United States United States
    Peptide Solution

    It was very easy to use and felt good on my skin. However I did not see the fantastic results that I was led to believe would happen. I will continue to use it until gone however because of cost am unable to probably order this item again. I am using multiple products from Dr. Denese line and do love them. That being said I am a loyal client of Dr. Denese.

    SV
    11/02/2020
    Shirley V.
    United States United States
    Superb Solution!

    I simply love this product and feel it has made a huge difference for me with my skin tone, lines and keeping my skin feeling wonderful. Great product, truly one of my favorites for certain!

    P
    06/21/2020
    Patricia
    United States United States
    Fabulous!

    This product is fabulous! After two weeks, I saw the skin on my face and neck look smoother, firmer and younger. I use twice a day after cleansing as soon as my face is dry and as per instructions, before any other product.

    A Dr Denese SkinScience Customer
    SK
    05/02/2020
    Sue K.
    United States United States
    I love this product

    I noticed gradual improvement in the look and feel of my skin. It looks and feels so soft and fine lines virtually gone especially around the eyes. I only wish you would bring back SuperSundays so I could purchase more as this is a bit pricey!

    LM
    05/01/2020
    Lorene M.
    United States United States
    RN

    I love using this daily after I wash my face with Dr. Denese cleanser. It improves the quality of my skin and diminishes wrinkles. It is an excellent product. I follow with your other line of products that are excellent for my fair skin.