Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
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  • Doctor developed
  • Clinically tested
  • PETA cruelty free
  • Made in USA

Join 20 million+ women who have transformed their skin with Dr. Denese

Wrinkle Rx 76% Peptide Solution Concentrate

Shatter the industry standard with the ultimate structural intervention for your skin.

While premium luxury serums typically offer active peptide levels in the single digits, Wrinkle Rx™ delivers an unprecedented 76% peptide concentration. This clinical-grade, high-performance concentrate acts as a cellular messenger, literally teaching your skin how to act young again.

100%
saw visible improvement in crow's feet
100%
said it did the most for them of any serum they had used
90%
found it succeeded where other serums failed

Independent consumer study. See the studies

Size — 1 oz.
1 oz. $105.30
$105.30 $162
30-Day Money-Back Guarantee
Use the whole jar. If you don't see results, we refund you.

Product details

Why it is different

Formulated with an advanced, multi-tiered matrix of peptides and plant stem cells, it targets everything from superficial fine lines to deep-etched expression wrinkles.

Why You Need It:

  • The 76% Difference: A monumental leap in cosmetic chemistry, delivering a pure, highly concentrated dose of anti-aging science that vastly outperforms standard 5-9% formulas.

  • Comprehensive Wrinkle Repair: Powered by a full-spectrum peptide complex (Tri, Tetra, Penta, Hexa, Hepta, and Oligo) plus SNAP-8™ and SYN®-COLL to firm, smooth, and relax the look of static and dynamic lines.

  • Targeted Eye Rejuvenation: Exceptionally effective for the delicate, hard-to-treat eye contour.

  • Clinically Proven: In an independent study, 96% of subjects reported a visible improvement and change in lines and wrinkles, especially around the eyes.

Perfect For: Anyone experiencing fine lines, deep wrinkles, or loss of firmness, especially those looking for a dramatic visible improvement in the delicate eye area.

Dr. Denese Wrinkle Rx 76% Peptide Solution Concentrate
From the clinical testing of this product. Individual results vary.

Clinical studies

The results, by the numbers

Independent Consumer Study:

  • 100% subjects found: visible improvement in Crow's feet.

  • 100% subjects reported: that this serum did perhaps the most for them compared to all other serums they have ever used

  • 90% subjects found that this serum succeeded where others failed

Watch

Dr. Denese explains it herself

How to use

How to use

Usage:Apply once or twice a day to clean skin. Use it as your first layer of skin care. Follow with a heavier serum such as e.g. HydroShield. Follow with eye cream of your choice.

Free from: Parabens, sulfates, dyes, phthalates. No animal testing.

Ingredients

What is inside

Ingredients: Water, Cyclomethicone, Caprylic/ Capric Triglyceride, Glycerin, Dipropylene Glycol, Sodium Hyaluronate, Dimethicon/Vinyl Dimethicone Crosspolymer, PEG/PPG-19/19 Dimethicone, Hydrolyzed Rice Protein, Butylene Glycol, Lecithin, Acetyl Glutamyl Heptapeptide-1, Malus domestica fruit cell culture, Rh-Polypeptide-7, Tripeptide-1, Malus domestica fruit cell culture, Caprooyl- Tetrapeptide-3, Avena Sativa (Oat) Kernel Protein, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-8, Palmitoyl Tripeptide-5, Oligopeptide-4, Diacetyl Boldine, Adenosine, Arginine, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Guanidine, Glucose, Dextran, BIS-PEG-18 Methyl Ether Dimethyl Silane, Dimethiconol, PPG-26-Buteth- 26, PEG-40 Hydrogenated Castor Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Phosphate, EDTA, Sodium Chloride, Sodium Polyacrylate, Methyl Gluceth-20, Disodium EDTA, Carbomer, Polysorbate 20, Polysorbate 80, Xanthan Gum, Citrus Aurantium Amara (Bitter Orange) Peel Oil, Sodium Polyacry- late, PVM/MA Copolymer, Caprylyl Glycol, Phenoxyethanol.

  • Always Doctor developed
  • Always Clinically tested
  • Always Visible results
  • Always High percentages of actives
  • Always PETA cruelty free
  • Always Manufactured in USA

Sent in by customers

Their own photos, their own words

Photographs customers uploaded with their reviews, across the range. The words are theirs — shortened at a full stop where a card ran long, never rewritten.

Photographs and reviews submitted by customers and published with their permission. Individual results vary.

Dr. Denese Simple Steps skin care program

Where this product fits in your routine

Simple morning routine

  1. 1
    Build Lipid Barrier

    Keeps water from leaving the skin. Hydrated skin is healthy skin.

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  2. 2
    Protect & Correct

    SPF 30 or 40 — rain or shine, summer and winter. 90% of skin aging is caused by daily sun exposure.

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Simple evening routine

  1. 1
    Cleanse & Tone

    A pH-balanced, non-drying cleanser — skip the soap — then a toner for what it missed.

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  2. 2
    Exfoliate & Purify

    Stimulates cellular turnover and lets the actives that follow reach their destination.

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  3. 3
    Stimulate Cellular Performance

    A thin, water-consistency serum that encourages the skin's own collagen building.

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  4. 4
    Build Lipid Barrier

    Lipid-based serum with ceramides, retinol, antioxidants and essential fatty acids.

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  5. 5
    Seal & Maintain

    Finish with your night cream to seal the work in.

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Complete the routine

Award Winning Power Trio

The Firming Facial Pads, the HydroShield® Serum and the Hydrating Dream Cream as one starter kit.

$79$127
Shop the trio

Reviews

What customers say

A doctor formulated this, not a marketing team.

Who made it

A doctor formulated this, not a marketing team.

Adrienne Denese, M.D., Ph.D. — Harvard and Cornell trained, and one of the first physicians to specialise in anti-aging medicine. Every formula leaves SkinScience Labs with the highest percentage of active, bio-identical ingredients it can carry. Over 20 million products sold worldwide.

“I formulate for results, not for hope.”

Adrienne Denese, M.D., Ph.D.