Dr. Denese Med MD 33 Clinical Reserve Crème 3.4 oz.


19 Reviews

See what our Customers are saying about the Med MD 33 Clinical Reserve Creme


"I am soooo glad I tried this! I was very happy with what I saw and felt after using this after the 1st week. I would say the biggest result is firmness. My face feels firmer and looks firmer. Especially, around chin area and the jaw line. My pores look smaller, which I didn't expect from a cream, and my skin has a real nice youthful glow that I haven't had in a few years." Review by: MarkyTampa 

Best ever

"This is the most effective night cream I have ever used. Its the first time my husband remarked about how good my skin looks. Yahhhhh for me!" Review by: joiee 

Nothing compares to this

" I only wish I took before and after pictures because the firmness was greater than the pictures shown on TV. I have never had ANY product do what this does, hydrates and firms my face and jowls." Review by: London33 

What is it: Measurably increases skin tightness and elasticity in 28 days!  

Med MD 33 Clinical Reserve Creme was originally formulated for Dr Denese's own personal use. It contains 33 clinically tested, clinically proven ingredients, many times more than even the most expensive creams on the luxury market today. Usually, even the most expensive luxury creams contain only a handful of active ingredients, this cream has 33!  No expense was spared when this cream was created, it was an experiment. It is a powerhouse night cream! It dramatically improves the look of lines and wrinkles, brightness, evenness, firmness and pores. It measurably and statistically significantly  increases skin tightness and skin moisture level in 28 days

Who is it for: Those who have lost firmness to the skin; have fine lines and wrinkles; uneven, dull skin tone; poor skin texture; enlarged pores; and visible, dry lines.

Why is it different: Med MD 33 Clinical Reserve Creme is formulated with 33 cosmetically relevant ingredients. It dramatically improves the look of fine lines and wrinkles; improves skin brightness and evenness, giving skin a more vibrant and youthful glow; it measurably  improves  firmness tightness  and improves pore size. EXPECT RESULTS!

Clinical Studies:

Independent Instrumental Clinical Novometer Study

  •  a statistically significant increase in moisture and hydration level in 28 days

Independent Instrumental Clinical Cutometer study

  • a remarkable Statistically significant increase in skin tightness and elasticity in 28 days. 

Usage: Apply at night as your final step of your skin regimen.

Made without parabens. No Animal Testing.
3.4 oz.


Ingredients: Water (Aqua), Butylene Glycol, Butyrospermum Parkii (Shea Butter), Steareth‐21, Dimethicone, Di‐C12‐15 Alkyl Fumarate, Cyclopentasiloxane, Squalane, Pentaerythrityl Tetraethylhexanoate, Steareth‐2, Glycerin, Methyl Glucose Sesquistearate, Stearyl Olivate, Octyldodecyl Olivate, Stearyl Dimethicone, Simmondsia Chinensis (Jojoba) Seed Oil, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Polymethacrylate, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide‐7, Palmitoyl Tripeptide‐38, Heptapeptide‐15 Palmitate, Copper Heptapeptide‐14 Pantothenate, Ascorbyl Methylsilanol Pectinate, Globularia Cordifolia Callus Culture Extract, Hydroxypropyl Cyclodextrin, Tocopheryl Acetate, Dipotassium Glycyrrhizate, Adenosine, Arginine, Foeniculum Vulgare (Fennel) Fruit Extract, Humulus Lupulus (Hops) Extract, Melissa Officinalis Leaf Extract, Viscum Album (Mistletoe) Leaf Extract, Chamomilla Recutita (Matricaria) Flower Extract, Achillea Millefolium Extract, Aloe Barbadensis Leaf Extract, Hydrolyzed Wheat Protein, Hyaluronic Acid, Phytic Acid, Triticum Vulgare (Wheat) Germ Oil, Linoleic Acid, Linolenic Acid, Sorbitol, Tocopherol, Urtica Dioica (Nettle) Extract, Equisetum Arvense (Horsetail) Extract, Cucumis Sativus (Cucumber) Extract, Centella Asiatica Extract, Chlorella Vulgaris Extract, Hydrolyzed Algin, Allantoin, Acetamide MEA, Panthenol, Beeswax, Sodium Stearoyl Glutamate, Dimethiconol, Polysilicone‐11, Lactic Acid/Glycolic Acid Copolymer, Dextran, Mica, Titanium Dioxide, Iron Oxides, Acrylates/C10‐30 Alkyl Acrylate Crosspolymer, Carbomer, Xanthan Gum, Polysorbate 20, Polysorbate 60, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.

Customer Reviews

4.9 Based on 19 Reviews
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Roseann S.
United States United States

Reserve Creme

When I use this cream it helps with all lines and wrinkles, and I also feel up firming effect. This is one of my favorites.

Cathey O.
United States United States

Perfect night cream

I’ve been using this cream at night for over 3 years and love it. It absorbs quickly, NEVER irritates, and leaves my skin soft supple and nourished. I recently had a looong (1.5 hour) dental procedure and the dental assistant admitted she had sneaked a look at my chart to see what my age was because my skin looked so good… she couldn’t believe I was 66!

Kennette G.
United States United States

My Favorite Moisturizer

When I heard that Dr. Denese created this moisturizer for her own use, it was one I had to try. It did not disappoint. Not only does this moisturizer feel fabulous by providing moisture and hydration to perfection, it has drastically improved my skin in every way possible. My skin looks brighter, with a subtle glow that does not come from makeup, it is more firm, elastic, less wrinkled and I no longer have visible pores since using it. I highly recommend this moisturizer if you want serious results.

Marsha P.
United States United States

One of My Favorite Dr. D. Night Cremes!

I love Dr. D. MD 33 Clinical Reserve Creme! I alternate this night cream with the Night Dream Cream and it works very well. I definitely recommend, I've been using this cream for several years!

Marlene L.
United States United States


I like the texture and absorption of the cream. It does help soften those age lines, giving a youthful appearance.

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