Dr. Denese Wrinkle Lost Line Reducer
Dr. Denese Wrinkle Lost Line Reducer
Dr. Denese Wrinkle Lost Line Reducer
Dr. Denese Wrinkle Lost Line Reducer
Dr. Denese Wrinkle Lost Line Reducer
Dr. Denese Wrinkle Lost Line Reducer
Dr. Denese Wrinkle Lost Line Reducer
Dr. Denese Wrinkle Lost Line Reducer

Dr. Denese Wrinkle Lost Line Reducer


Regular price $ 59.00
Save $ -59.00
1135 in stock
Wrinkle Lost: the 3 Minute Age Eraser that makes you look about a decade younger instantly, lasts all day, does not fade, does not crack and does not turn white on you. Temporary? Yes but so is make up… Invisible, unique silk fiber web that holds your skin in place, does not allow it to descend, gather and form wrinkles. In a consumer study, 100% of subjects agreed that Wrinkle Lost smooth the appearance of fine lines and wrinkles.


Who is it for: Anyone who earned a few lines and wrinkles around the eyes, mouth and anywhere in between. 

Why is it different: As we grow older, our skin starts to collapse, starts to descend and gather in places like under the eyes, around the nasolabial fold, corner of the mouth, generating wrinkles. You can think of Wrinkle Lost as an invisible scaffolding to support and hold up your skin.

Wrinkle Lost is based on our unique proprietary SILK PROTEIN FIBER Technology that creates an INVISIBLE FIBER WEB to hold your skin in place, to act like an invisible scaffolding to keep your skin in place so it does not descend and form wrinkles in places where it gathers e.g. under the eyes.

It performs double duty as well: it acts like your eye cream, face cream with important natural ingredients such as: Coffee Extract, Acai Extract, Goji Extract, Noni Fruit, Pomegranate, Green Tea, Mangosteen Extract plus the best of science such as Hyaluronic acid to plump and Hexapeptide 8, Tetrapeptide 2 to address lines and wrinkles.

See what some of our QVC Customers had to say about this product:

"Finally a product that works for me. I have tried every single one on QVC and this one works for me. No easy feat because I’m 75 years old! Thank you Dr Denese for this miracle formula!"

"I've tried multiple products from this category: none of them worked.

This one has an interesting structure. What worked for me is applying just a little amount of the product, almost a drop, and the results were great! Even my kids told me I look more refreshed and not tired. It is not a miracle in a bottle, but I love how it makes me look. I would definitely buy more in the future for those special days/occasions.

Suggestion: don't use a lof of this product. It becomes messy. A little goes a long way."

Clinical Studies

  • In a consumer perception survey of 25 participants, three minutes after using the product:
  • 88 percent agreed fine lines and wrinkles on the forehead are visibly improved
  • 88 percent agreed their overall skin has a youthful appearance.
  • 100 percent agreed the product smooths the appearance of fine lines and wrinkles.



    Usage: Apply in the morning or alternatively, apply Wrinkle Lost for special occasions only, when you will be photographed or seen by others who matter to you.

    Important tips for application: the product works the strongest if applied on clean dry skin. Any cream or lotion already on your face will dilute the effect because it will interfere with the formation of the fiber web.

    Some people find the full effect of Wrinkle Lost too strong, so they mix it with an eye cream or face cream in advance or apply Wrinkle Lost on a light cream layer on your face. Please note, Wrinkle Lost will be less effective this way but maybe this is all that you need. You have to experiment.

     If you want to have make up on your face, it needs to go on the skin before Wrinkle Lost and not after. Next, you need to wait about 20 minutes until it completely dries and settles into the skin. We recommend a solid compact foundation and not a liquid foundation because it settles into the skin faster.

     If you apply our SPF 40, please wait 20 minutes or so, until it completely dries on the skin surface. If you apply anything on top of Wrinkle Lost, the silk fiber web breaks and loses effectiveness to a varying degree.

    Alternatively: some customers find it helpful to apply a powder foundation on top of Wrinkle Lost for a light coverage.


    Ingredients: Water, Sodium Silicate, Magnesium Aluminum Silicate, Isopentyldiol, Silk, Sodium Hyaluronate, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-2, Magnesium Gluconate, Lycium Barbarum (Goji) Fruit Extract, Coffea Arabica (Coffee) Seed Extract, Euterpe Oleracea (Acai) Fruit Extract, Morinda Citrifolia (Noni) Fruit Extract, Punica Granatum (Pomegranate) Extract, Camellia Sinensis (Green Tea) Leaf Extract, Garcinia Mangostana (Mangosteen) Fruit Extract, 1,2-Hexanediol, Caprylyl Glycol, Sodium Benzoate, Phenoxyethanol, Sorbic Acid, Mica, Iron Oxides, Titanium Dioxide

    Why in this order?

    Based on state-of-the-art medical knowledge, I have identified six phases of skin care that you will need to complete every night to successfully address the eight visual signs of aging skin.

    1. Cleanse and Tone

    The cleansing phase is an important first step and I do not recommend using soap. The pH of soap can dry your skin. I also do not recommend water-free, leave-on cleansers, which can clog your pores. A good cleanser has a pH close to that of the skin and will not dry out your skin. After cleansing, I recommend using toner to remove the dirt the cleanser missed.

    CLEANSER: The best ingredients to seek out in this product are alpha- and beta-hydroxy acids, which are excellent cleaning agents, and other beneficial additions, such as vitamins C and E. However, the key isn't just the ingredients—you rinse them off very quickly—but finding a good cleanser that doesn't leave your skin feeling tight and dry. You should judge your cleanser based on the condition of your skin after you've washed, rinsed, and dried. Your face should feel fresh, clean, and comfortable, not dry or pulled.

    TONER: The same criteria apply. An effective toner will have a gentle astringency, yet it should leave your face feeling soft and refreshed. If your skin doesn't feel pulled and dry after you've applied it, it's the right product for you.

    2. Exfoliate and Purify

    The exfoliating phase is critical if you want flawless skin. Exfoliation stimulates cellular turnover and may improve skin thickness. It also removes dead cells on top of your skin, allowing skin care products to transport key ingredients to their destination. The exfoliating phase also provides one final opportunity to open up clogged pores before you move on to the other phases of your skin care routine.

    Try our glycolic acid peel pads, the Advanced Firming Facial Pads, with a 10 % strength solution. Clinical studies have shown significant collagen-stimulating and skin-thickness-building action at the right glycolic concentration at the right pH levels. Our Advanced Firming Facial Pads are made to these exact specifications. These pads also exfoliate your skin to perfection which is critical if you want flawless skin.

    Microdermabrasion Cream: You need this product for additional exfoliation once a week, or twice, if your skin has the tolerance for it. A good microdermabrasion cream should have a rich texture and contain abrasive particles—aluminum oxide or pumice is ideal—but the particles should be very small. Avoid products that contain large grains of any rough or sharp particles. The purpose of this step is to micropolish your face, not scratch it. And the cream should feel good. When you rinse it off, your face should not feel tight or dry, but rather smooth, soft, and soothed.

    3. Stimulate Cellular Performance

    SKIN-STIMULATING SERUM: The skin-stimulating phase encourages the skin's own collagen-building machinery and repair mechanism to soften the look of lines and wrinkles. This is ideally done with a thin water-consistency serum, rich in ingredients that easily permeate the skin. This step does not feel particularly moisturizing and it may leave your skin feeling dry and tingly.

    4. Build Lipid Barrier

    SKIN-BUILDING SERUM: The skin-building phase helps restore skin barrier functions via delivering essential nutrients to the skin. This is ideally done with lipid-based serums and contains high concentrations of lipid (fat) soluble vitamins, ceramides, antioxidants, retinol and essential fatty acids.

    With this regimen you are layering your face with all the rich ingredients that are so effective in fighting the signs of aging. You are rebuilding the all important skin lipid barrier to protect your skin from drying out and generating wrinkles.

    5. Seal and Maintain

    The skin-building phase helps prevent water loss via sealing the top layer of the skin with emollient lipids (step 4) while the skin-sealing phase (step 5) moisturizes and prevents water loss by sealing the skin. This is done with a cream with the right balance of lipids and humectants to help maintain and balance the moisture level in the skin to protect the skin from dryness.

    This final application of cream is to seal the skin and rebuild the lipid barrier. First and foremost, a cream should feel good. It should not leave your skin feeling dry and your skin should not remain shiny for hours after you've applied it. Look for the right level of lipids in the cream that is satisfying to your skin. Ceramides, EFAs, retinol, vitamins C and E, and hyaluronic acid are all excellent ingredients for this last step in your skin care program.

    6. Protect and Correct

    The skin-protection phase consists of using SPF 30 sun protection daily in the morning and throughout the day, rain or shine, every day of the year. Sun exposure is the most common cause of aging and with use of a good protective product, aging from sun damage can be reduced.

    Doctor Developed. Clinically Tested. Visible Results.
    High Percentages of Active Ingredients.
    PETA Cruelty Free. Manufactured in USA. 
    Free from:
    • Parabens 
    • Sulfates 
    • Dyes 
    • Phthalates
    • Formaldehyde
    • Mineral Oil
    • Triclosan 
    • Hydroquinone 
    • SLS & SLES
    • Oxybenzone

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