Pro Peptide Gel and 76% Peptide Solution.They are both highly potent and they both work well. Their main function is to stimulate collagen production in the skin cells, which diminishes deep, expression lines such as the nasolabial folds (smile lines), the deep 11 lines in between your brows, forehead lines and even the lines above your lip (commonly called smoker's lines). Both address firming through activating the skin's own cellular mechanism to stimulate collagen. Now on to the differences. The 76% Peptide Solution has more than three times the amount of peptides than the Pro Peptide Gel. More peptides means faster results. The 76% Peptide Solution is a serum-like product that you apply to your entire face, concentrating on the lines, day or night or both (depending on your needs). On the other hand, the advantage of the Wrinkle Rx Pro Peptide Gel is that it contains 15% of stabilized Vitamin C in addition to a generous amount of peptides. This is a gel like product that will address the look of deep etched in lines as well but in addition, it will help brighten dull, uneven skin tone. Wrinkle Rx Pro Peptide Gel can also be used day or night or both and is also applied to the entire face concentrating on the problem areas. Both products are applied after cleansing and after exfoliation and before any other serums or creams. Both are good for all skin types. If you decide to use both, please use one in the morning the other at night. Which one you choose to incorporate into your regimen depends on how important of a concern deep lines and firming are to you as well as your budget.